One of the first stages of atherosclerosis is when deposits such as cholesterol accumulate on the inner arterial walls.
Tocotrienols have the propensity to reduce the ability of the cell lining to bind with monocytes. This reduces the risk of developing atherosclerosis. 
Tocotrienols are shown to reduce the blockage of the carotid artery (artery supplying oxygen to the brain) in humans in a 4-year study. 88% of patients who had been given tocotrienol supplementation showed improvements in their carotid artery condition.