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Benefits of Tocotrienol
    Powerful Antioxidant
    Good for your heart
    Reduces Altherosclerosis
    Inhibits Platelet Aggregation
    Protects against Cancer
    Protects Neural Cells
    Reduces Risk of Diabetes
    Protects Skin/Anti-aging
    Maintains Eye Health
    Prevents Hair Loss
    Repairs Muscle
    Enhances Immunity & Maintains Health
       
References
       
       
 
References
 
1. Ikeda, S, et al. (2000). Selective uptake of dietary tocotrienols into rat skin. Journal of Nutritional Science and Vitaminology, 46, 141-143.

2. Packer, L., Weber, S.U., Rimbach, G. (2001). Molecular aspects of alpha-tocotrienol antioxidant action and cell signaling. Journal of Nutrition, 131 (2), 369S-373S.

3. Pearce, B.C., Parker, R.A., Deason, M.E., Qureshi, A.A., Wright, J.J. (1992). Hycholesterolemic activity of synthetic and natural tocotrienols. Journal of Medicinal Chemistry, 35 (20), 3595-3606.

4. Qureshi, A.A., & N. Qureshi. (1993). Tocotrienols: Novel hypocholesterolemic agents with antioxidant properties. In L. Packer and J. Fuchs (ed.), Vitamin E in health and disease (p.247). Marcel Dekker, New York.

5. Newaz, M.A., Nawal, N.N. (1999). Effect of gamma-tocotrienol on blood pressure, lipid peroxidation and total antioxidant status in spontaneously hypertensive rats (SHR). Clinical and Experimental Hypertension, 21 (8), 1297-1313.

6. Rasool, A.H.G., Yuen, K.H., Yusoff, K., Wong, A.R., Rahman, A. R. (2006). Dose dependent elevation of plasma tocotrienol levels and its effect on arterial compliance, plasma total antioxidant status, and lipid profile in healthy humans supplemented with tocotrienol rich vitamin E. Journal of Nutritional Science and Vitaminology, 52 (6), 473-478.

7. Theriault, A., Chao, J.T., Gapor, A. (2002). Tocotrienol is the most effective vitamin E for reducing endothelial expression of adhesion molecules and adhesion to monocytes. Atherosclerosis, 160 (1), 21-30.

8. Kooyenga, D.K., Watkins, T. R., Geller, M., Bierenbaum, M. L. (2001). Antioxidants modulate the course of carotid atherosclerosis: A four-year report. In K. Nesaretnam and L. Packer (Ed.), Micronutrients and health: molecular biological mechanisms (p. 366-375). Illinois, IL: AOCS Press.

9. Miyazawa, T., et al. (2009). Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol). Journal of Nutritional Biochemistry, 20 (2), 79-86.

10. Kline, K., Yu, W., Sanders, B.G. (2001). Vitamin E: mechanisms of action as tumor cell growth inhibitors. Journal of Nutrition, 131 (1), 161S-163S.

11. McIntyre, B.S., Briski, K.P., Abdul, G., Sylvester, P.W. (2000). Antiproliferative and apopotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelical cells. Proceedings of the Society for Experimental Biology and Medicine, 224 (4), 292-301.

12. Sylvester, P.W, Shah, S.J. (2005). Mechanisms mediating the antiproliferative and apopotic effects of Vitamin E in mammary cancer cell. Front in Bioscience, 10, 699-709.

13. Malafa, M.P., Sebti, S. Delta-Tocotrienol Treatment and Prevention of Pancreatic Cancer. US Patent 20080004233. 3 January 2008.

14. Traber M.G., et al. (1997). Diet-derived and topically applied tocotrienols accumulates in the skin and protected the tissue against UV light-induced oxidative stress. Asia Pacific Journal of Clinical Nutrition, 6 (1), 63 –67.

15. Michihara, A., et al. (2009). Delta-tocotrienol causes decrease of melanin content in mouse melanoma cells. Journal of Health Science, 55 (2), 314-318.

16. Khanna, S., et al. (2005). Neuroprotective properties of the natural vitamin E alpha-tocotrienol. Stroke, 36 (10), 2258–2264.

17. Sen, C., Khanna, S., Roy, S., Packer, L. (2000). Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. Journal of Biological Chemistry, 275 (17), 13049-13055.

18. Kamat, J.P., Devasagayam, T.P.A. (1995). Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria. Neuroscience Letters, 195 (3), 179-182.

19. Holub, B. (1989). Inhibition of Platelet Aggregation by Tocotrienols. University of Guelph, Ontario, Canada. Internal Publication.

20. Miyazawa, T., et al. (2009). Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol). Journal of Nutritional Biochemistry, 20 (2), 79-86.

21. Shibata, A., et al. (2009). Delta-tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. Journal of Agricultural and Food Chemistry, 57(18), 8696-8704.

22. Stephen, D. (2009). Vitamin E may reverse male pattern baldness: Study. Nutraingredients.com. Retrieved March 22, 2010 from http://www.nutraingredients.com/Research/Vitamin-E-may-reverse-male-patternbaldness-Study.

23. Reznick, A. Z., Witt, E, Matsumoto, M, Packer, L. (1992). Vitamin E inhibits protein oxidation in skeletal muscle of resting and exercised rats. Biochemical and Biophysical Research Communications, 189 (2), 801-806.

24. Montonen, J., Knekt, P., Järvinen, R., Reunanen A. (2004). Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care, 27 (2), 362–366.

25. Budin, S.B., et al. (2009). The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats. Clinics (Sao Paolo), 64 (3), 235-244.

26. Adachi, H., Ishii, N. (2000). Effects of tocotrienols on life span and protein carbonylation in Caenorhabditis elegans. The Journals of Gerontology, Series A: Biological Sciences Medical Sciences, 55 (6), B280–B285.

27. Meydani, S.N., et al. (2004). Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial. Journal of the American Medical Association, 292 (7), 828-836.

28. Burton, G.W., et al. (1998). Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. American Journal of Clinical Nutrition, 67 (4), 669-683.

29. Qureshi, A.A, et al. (1996). Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-Hydroxy-3methylglutaryl Coenzyme A reductase activity in chicken. Journal of Nutrition, 126 (2), 389-394.

30. Kritchevsky, D., Chen, S.C. (2005). Phytosterols - Health benefits and potential concerns: a review. Journal of Nutrition Research, 25 (5), 413-428.

31. FDA Permitted Health Claims for Products Containing Plant Sterols.

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